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A history of hypertension was found to convey a protective effect (OR = 0.62, 95% CI = 0.52 to 0.73).
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These survival curves also underscore two other points: First, a HLA-B*57-containing genotype does not require the presence of a 'protective' HLA-C allele to convey a protective effect on disease progression.
Only one genetic variant was found to confer a protective effect following radiotherapy.
Hendershot and colleagues (2010) tested an intervention that targeted the ALDH2 genotype, found almost exclusively in individuals of northeast Asian descent, which can convey a protective effect against alcohol misuse.
Folate depletion appears to enhance carcinogenesis, whereas folate supplementation may convey a protective effect (Kim, 1999).
However, this is proving to be an immensely complex task because it is difficult to predict which immunological response(s) in candidate vaccine-challenged animals or in vitro studies will convey a protective effect in humans [1], [2], [3].
Previous association studies also suggest that serogroup HLA-A10 may convey a protective effect [46].
Cesarean section was found to have a protective effect on neonatal mortality rates.
A history of hypertension conveying a protective effect was an unexpected result on multivariate analysis.
Recent studies have isolated the farm, rather than the general rural environment as the factor conveying a protective effect against atopy.
Unlike previous reports, we found evidence suggesting a protective effect of influenza vaccination on GBS risk.
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