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Both MX1 and IFI-27 are type 1 interferon target genes previously also found to be upregulated in psoriatic skin lesions [16].
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S100A7 protein, with a molecular weight of 11.4 kDa, was found to be upregulated in skin lesions of psoriatic patients [17].
MMP-9 is a protease found to be upregulated in virtually all malignant tumors.
We focused on Lipocalin2 (Lcn2), a protein recently found to be upregulated in several neuroinflammatory contexts.
MiR-24 is found to be upregulated in differentiated cells.
Socs genes were found to be upregulated in other autoimmune inflammatory diseases, such as Socs3 in T cells from the colon mucosa of patients with Crohn's disease [ 31] and over-expression of SOCS1, SOCS2 and SOCS3 in the epidermis of psoriatic skin lesions, as well as in vitro stimulation with interferon-γ induced Socs1 and Socs3 expression in keratinocytes [ 32].
RAGE expression was found to be upregulated in diabetic animals.
GRIA2 was found to be upregulated in chemosensitive tumours.
Caspase-3 was found to be upregulated in HD patients.
Got1 and Aurka were found to be upregulated in DDLPS.
In parallel, Par-4 was found to be upregulated.
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