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It regulates approximately 200 numbers of proteins known as client proteins including large number of oncoproteins found to be upregulated in many cancer cells.
The Pim proteins (1, 2 and 3) are serine/threonine kinases that have been found to be upregulated in many hematological malignancies and solid tumors.
YY1 itself has been classified as an oncogene and was found to be upregulated in many cancer types.
FOXM1 was characterized as a proto-oncogene, and was found to be upregulated in many types of cancer, including prostate tumors (Kalin et al., 2006).
C6orf173, which is also known as CUG2 or CENP-W, is a novel oncogene that has been found to be upregulated in many human cancer tissues.
It is found to be upregulated in many cancers of other tissues and linked to tumour angiogenesis (Plate et al, 1993; Zanetta et al, 2000; Franchini et al, 2013), Thymidine phosphorylase (TP) is overexpressed in RCC (log2 fold change=2.89, FDR-adjusted P=4.48E−18).
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Actually, many genes have been found to be upregulated in the transgenic plants.
Expressions of many cyclic nucleotide-gated ion channels (CNGC) were found to be upregulated in both the leaves and the roots of B. napus.
We focused on Lipocalin2 (Lcn2), a protein recently found to be upregulated in several neuroinflammatory contexts.
MMP-9 is a protease found to be upregulated in virtually all malignant tumors.
The growth arrest-specific 2 (GAS2) was cloned and found to be upregulated in the feces of recurrent CRC patients.
More suggestions(15)
found to be amplified in many
found to be mutated in many
found to be enriched in many
found to be upregulated in interdigital
found to be elevated in many
found to be upregulated in colorectal
found to be upregulated in diabetic
found to be upregulated in differentiated
found to be upregulated in prediatric
found to be upregulated in osteoarthritic
found to be implemented in many
found to be inactivated in many
found to be involved in many
found to be upregulated in diseased
found to be upregulated in psoriatic
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