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This situation can be remedied by increasing the hydrophobicity of AMPs, although AMPs of higher hydrophobicity have been found to be less selective in their action, and to display increased toxicity [21].
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The mono-protection step was found to be less selective than in the case of the Boc-procedure employed for the synthesis of 6 (see Scheme 1) and even when only 0.4 equiv.
As expected, thiourea-containing 1d was found to be less selective (Table 1, entry 25), although this was less pronounced than in the previous experiments.
55 In one clinical study, however, BPSA medium was found to be equivalent to ASH in its ability to grow B. pseudomallei but also found to be less selective.
The co-reduction of mixed ions is known to be less selective in core shell synthesis.
Systematic vaccination against MMR was found to be 4 5 times less expensive than selective vaccination, while selective vaccination of seronegative individuals was more cost-efficient for varicella.
COX-2-selective NSAIDs (eg. Celecoxib, Meloxicam) which have less side effects, are not found to be better for the treatment of TMD.
The most selective inhibitor in the screen was found to be PCI34051, an HDAC8 inHDAC8or38.
Texas A&M is one of the most selective schools in its region, so it is likely to attract many top firms; Penn State, which is less selective than many other schools in Pennsylvania, is unlikely to attract as many firms.
Due to a higher grazing pressure, grazing is less selective.
36 Dapagliflozin is less selective for SGLT2 over SGLT1 in rats (206×) compared with humans (1400×).
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