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Metal-binding sites together with Arg418 in the large-binding pocket of the enzyme were found to be indispensable for catalytic ability.
Reducing the intra-specific variability by using a particular sub-group within each tested factor (except acclimation time) was found to be indispensable for a successful feeding assay with individual organisms.
Interaction plots were found to be indispensable both in clearly presenting and understanding the complex relationships seen in the data, and in interpreting the results in terms of a number of practical engineering conclusions.
Consideration of non-linearity is found to be indispensable in the case of earthquake excitation, with a low dominant frequency, since the non-linear analysis leads to positive values of the mean responses of the liquid surface and wall displacement, while the linearized theory predicts zero mean response.
Both PLpro-TM and STING are membrane-bound proteins that are anchored to the endoplasmic reticulum (ER) membrane with the transmembrane (TM) domain (Huang et al., 2012; Ouyang et al., 2012; Shang et al., 2012; Shu et al., 2012; Yin et al., 2012), and the TM domains at the N-terminus of STING were found to be indispensable for IRF3 activation in vitro (Tanaka and Chen, 2012).
Other virulence factors were found to be indispensable for Y. pestis pathogenesis via the s.c. route of infection.
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In addition to this inductive component, constitutive autophagy has been found to be an indispensable mechanism in terminally-differentiated cells such as neurons in order clear up damaged long-lived nuclear and cytosolic proteins or organelles.
I find mine to be indispensable.
Findings and Conclusions This evaluation found the role of UNICEFs Western and Central Africa Regional Office, WCARO, to be indispensable.
SPO11 appears to be indispensable for meiosis since homologs have been found in all eukaryotes examined to date [ 59, 79].
We found treatment with BMP4 in phase 1 and VEGF-A in phase 2 to be indispensable for endothelial differentiation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com