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All other compounds found to be inactive.
The other compounds were found to be inactive.
But both the compounds were found to be inactive against Plasmodium falciparum.
Both the saturated and unsaturated phenolic furanocoumarin derivatives were found to be inactive.
Target 4 was found to be inactive and to lack cytotoxicity to the host cells.
The mutants H200A, K308A, Y312A, Y312F, and W165A were found to be inactive or almost inactive.
At pH 8.5 the mononuclear complex 4 was found to be inactive.
Metabolites 2 and 3 were found to be inactive, while metabolite 4 only weakly inhibited the enzyme.
Surprisingly, the enzyme was found to be inactive even after the removal of the N-terminal His-tag.
All compounds were found to be inactive against AChE, while metabolite 5 7 have significantly inhibited the BChE.
Mutants H183A and N202A were overexpressed and were found to be inactive at the cell lysate level (Table 2).
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