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Epidermal Growth Factor Receptor-2 (HER-2) and Estrogen receptor-alpha (ER-α) have been found to be dysregulated in several types of cancer.
Integrins, a family of transmembrane proteins, have been found to be dysregulated in several varieties of cancer as well as in other disorders such as inflammation and fibrosis.
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In this study, we focused on miR-381, which is found to be dysregulated in various tumors [ 10, 11].
More interestingly, several human miRNAs sharing seed sequences with EBV miRNAs were found to be dysregulated in NPC tissues, providing a potential linkage between EBV miRNAs and human malignancy.
LncRNAs have been found to be dysregulated in a wide range of human diseases and disorders, including various cancers.
Several key genes and miRNAs related to hematopoiesis, vascular development and apoptosis were found to be dysregulated in RPS24-deficient zebrafish.
Interestingly, many of these human miRNAs have been found to be dysregulated in human malignancies, including NPC.
Oftentimes, miRNAs levels are found to be dysregulated in cancer patients.
The latter signaling pathway has been found to be dysregulated in the AD brain.
Another miRNA found to be dysregulated in all types of samples studied here were both strands of miR-143.
The transcription factor NF- κB is central to inflammation and has been found to be dysregulated in muscular dystrophy.
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