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Cks1 was found to be an essential cofactor for efficient Skp2-dependent ubiquitination of p27Kip1.
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Very recently, glutathione (GSH), either generated by bacteria or derived from host cells, was found to be the essential small molecule cofactor of PrfA through allosteric binding to the protein (Reniere et al., 2015).
Magnesium, found in whole grains, is an essential cofactor for multiple enzymes involved in glucose metabolism (2).
Doyle, E.L. et al. CD63 is an essential cofactor to leukocyte recruitment by endothelial P-selectin.
Although B12 is an essential cofactor for methionine synthase, the enzyme that catalyzes the remethylation of homocysteine to methionine, we found no increase risk for skin lesions among individuals with low B12 concentrations.
Results suggest Mg2+ is an essential cofactor for chelating inhibitors.
Biochemical studies using the purified protein revealed that guanosine triphosphate (GTP) is an essential cofactor for the reaction.
Tetrahydrobiopterin (BH4) is an essential cofactor for various enzymes in mammals.
Among these molecules, carnitine is an endogenous amine which is an essential cofactor for mitochondrial β-oxidation.
Copper (Cu) is an essential cofactor for a variety of metabolic functions, and the regulation of systemic Cu metabolism is critical to human health.
Tetrahydrofolate is an essential cofactor required for metabolic reactions involving one-carbon transfer.
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