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While our prescription claims-based measure of adherence has been found to be a valid proxy for actual medication-taking behaviour, we had no measure of actual patient adherence (ie, daily ingestion/consumption) to the prescriptions they filled.
In contrast, a study in Boston, among 746 children at the age of 3 years, showed no association of maternal smoking during pregnancy with central adiposity, measured by the subscapular and triceps ratio, which has been found to be a valid proxy for intra-abdominal adipose tissue among children [ 15].
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The PedsQL, including by parent proxy report, has been found to be a valid and reliable tool in pediatric rheumatology [23].
This has been found to be a valid approach [ 31].
By comparing P fractions of soil and recent lake sediment samples, these fractions are shown to be a valid proxy for landscape-scale nutrient status.
Due to these results bedtime exposure levels were not considered to be a valid proxy of night time exposure.
In this study, we included treatment with inotropes/vasopressors that we expect to be a valid proxy for shock.
Age and number of drugs used, which has been shown to be a valid proxy measure for overall comorbidity, were included in the analyses as continuous variables.
Because its primary source is traffic emissions, NO2 is considered to be a valid proxy for exposure to air pollution from traffic.
Therefore bedtime exposure levels were not considered to be a valid proxy of night time exposure and had to be excluded from the analyses [ 22].
The TUG is a proxy of household mobility and has been found to be reliable and valid in a variety of older populations [ 31, 32].
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