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The growth ratio parameter, a non-intrusive size analysis of the same spheroid before and after exposure to drugs, was found to be a sensitive indicator for the reaction of MCF7 breast cancer spheroids to cytotoxic drugs.
The chlorophyll fluorescence transient has been found to be a sensitive indicator of photosynthetic electron transport processes (Tóth et al. 2007).
The kidney slice technique has been found to be a sensitive indicator in the assessment of halogenated hydrocarbon-induced nephrotoxicity.
The OJIP transient has been found to be a sensitive indicator of photosynthetic electron transport processes [ 29].
Enhanced PAH transport has been found to be a sensitive indicator of gentamicin induced nephrotoxicity, while inhibition of other parameters has been reported.
Of the various clinical responses, PASI 50 was found to be a sensitive indicator of reduced radiographic progression in patients with PsA treated with adalimumab for 24 weeks.
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In our studies, we have found βgal expression in the FTL mouse brain to be a sensitive indicator of brain state.
The KSS scale has been proven to be a sensitive indicator and is well validated [25].
SCE was found to be the most sensitive indicator of arsenic exposure because it was the only biomarker that displayed a statistically significant difference between the internal and the external control groups (Table 1).
Diploid males have been found to be sensitive indicators of the loss of genetic diversity in Hymenoptera.
Cough has been previously found to be one of the most sensitive clinical indicators of influenza, but has little specificity, whereas fever is a classically-cited characteristic of influenza, with substantial positive predictive value, but lower sensitivity [ 34].
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