Sentence examples for found to be a negative regulator from inspiring English sources

Using a selection of specific signaling pathway inhibitors, it was found that PI3K-, PKC- and p38-MAPK pathways positively regulated chondrogenesis while the ERK-pathway was found to be a negative regulator in staurosporine-induced re-differentiation, whereas down-regulation of ILK by siRNA indicated that ILK is not determining for chondrocyte re-differentiation.

Mlo is found to be a negative regulator of defense-responses and/or cell death such that the null mlo alleles mediate resistance by allowing an elevated level of defense responses to occur constitutively during infection by pathogen, a function that is dependent on Ror1 and Ror2 (required for mlo-specified resistance)(Anderson et al. 2005; Peterhansel et al. 1997).

Latexin has been found to be a negative regulator of the size of the haematopoietic stem cell population in mice [37].

GA3 was found to be a negative regulator and resulted in low levels of mRNA transcripts.

In particular, miR-27a was found to be a negative regulator of adipogenesis via the suppression of PPARG expression [ 13].

In summary, DUSP1 was found to be a negative regulator for the production of inflammatory cytokines [ 55].

p53 has also been found to be an upstream negative regulator of Plk4 via histone deactylation (HDAC) [ 21].

Specifically, adiponectin has been found to be an important negative regulator of hematopoiesis and the immune system (Yokota et al, 2000).

In addition, the PRKC apoptosis WT1 regulator gene (PAWR), known to act as a negative regulator of proliferation [ 42], was found to be down-regulated.

In addition, Tamo, which is a negative regulator for nuclear import of Dorsal, was found to be one of the down-regulated DEGs.

Neuronal CD200 is a negative regulator of inflammation, previously found to be decreased AD [ 120] and PD [ 121].