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We found normalization factors of 0.9359472 and 1.0684363, respectively.
We found normalization had significant effects on the distribution of the read counts (Additional file 12).
For leaf libraries we found normalization allows partial recovery of expression strength aside the desired effect of increased coverage.
While abnormal liver function enzymes typically improve with treatment, in our review of 20 HIV-infected hepatic TB patients, we found normalization of liver enzymes lagged by months to years behind the clinical resolution [ 30].
We found normalization of L-type Ca2+ channel activity with unloading, which is due either to new t-tubules containing L-type channelsnnels or to increased conductance amongst existing channels.
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In order to find normalization genes for qPCR verification, we looked for genes that showed no differential expression in any of the eight stages analyzed.
Further, untreated HIV infected persons show signs of increased fibrinolysis with increased d-dimer [ 15] and some studies find persistently elevated levels after cART [ 18] whereas others find normalization of D-dimer with cART [ 10].
On the other hand, the worst AUC median (0.55 ± 0.19) was found without normalization (normalization 'none') and when only the 18 stereospecific probes (stereospecificity 'unique') were used.
Therefore we present results taking the 75% count as the normalization factor since Bullard et al. found this normalization scale to have less bias in fold-change estimates and better sensitivity and specificity than none or total lane count.
They found that normalization with the age-specific template led to significantly different tissue distributions than normalization with the adult template.
Watkins and Makin (1994) found that normalization can also be observed with filtered precursor sentences that are played backward and that the amount of normalization is not reduced in this case.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com