Keenan and Esteban found no outcome improvement in patients treated with NIV who developed ARF in the following 48 h after extubation when compared with standard medical therapy [ 8, 9].
We found no effect on outcome nor any correlation to Delta-He in this cohort.
This generic nature of the EAP may be the reason that we found no effect on outcome.
Moreover, observational studies cannot prove causation and most intervention studies found no effect on outcome even where studies indicated a potentially important mechanism, for example, HDM interventions.
One study evaluated the use of defibrillators on emergency medical services and found no effect on patient outcomes [ 13].
Trials on magnesium treatment starting < 4 days after symptom onset found no effect on poor outcome or DCI in SAH.
This IV found no effect on the outcome but did find variations in the treatment exposure due to the countries' own policies regarding ICU admission.
We found no significant outcome differences between both treatment modalities.
A considerable number of these studies found no improved outcome [ 14, 16, 22].
Although our results are based on retrospective findings and are in small numbers, we found no improved outcome for women with early-stage disease undergoing surgical castration and pelvic lymphadenectomy.
