Sentence examples for found in linkage with from inspiring English sources
More recently, mutations associated with both hereditary and sporadic neuroblastoma were discovered in the ALK tyrosine kinase [3], [21], a gene mapping to a region previously found in linkage with NB [3], [22].
However, it is worth noting that this allele was found, in most cases, in linkage with DRB1*15, whereas in the controls, a larger proportion of DQB1*0602 was found in linkage with DRB1*11 alleles.
However, in H. didactylus, the U2 was not found in linkage with any other U snRNA; this absence is, so far, the only instance found within a fish group.
DRB1*15 alleles are found in linkage disequilibrium with DQB1*0602.
Analyses of other genes in the MHC complex found in linkage disequilibrium with the DRB1*13 alleles may also give insight to this protective effect.
Not much is known on the biological function of KIR receptors and for now no direct connection has been seen between KIR genes and MS. However, they cluster on Chromosome 19q13.4, a region previously found in linkage studies to be associated with MS[52].
While no evidence of linkage to the Vra2 region was found in G8, linkage with a LOD score of 2.39 for the max marker (D5Rat190) was found in the G10 cohort (Fig 3A).
Additive and dominant QTLs were found in tight linkage with SSR markers tested for drought tolerance in E. grandis × E. urophylla hybrid clones (Teixeira et al. [2011]).
An example of such co-selection is loci that confer resistance to heavy metals, which are often found in close linkage with resistance loci (Baker-Austin et al. 2006).
It was proposed that the central region of the B complex could be considered as minimal and essential, as the limited number of class I and class II genes are found in tight linkage with other genes having functions in the immune response [ 44].
In the first stage, microsatellites were typed in the 17q11.2 region, previously independently found to be in linkage with MS. One significant association was found at microsatellite D17S798.
