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Studies at the University of North Carolina and the University of Michigan have found heightened rates of dementia and other cognitive decline, results corroborated by a New York Times demographic analysis of members of the league's 88 Plan.
For example, both Dr. Hoffman's group and a team led by Dr. Philip McGuire, a professor at the Institute of Psychiatry in London, found heightened activity in Broca's area, a region of the frontal lobe involved with speech perception and processing.
But if there was an absence of the topical dramas that flooded theaters in the first years after the invasion of Iraq ("Stuff Happens" at the National or "Guantánamo: Honor Bound to Defend Freedom" at the Tricycle), I was repeatedly stirred by productions that found heightened reflections of the present in the past.
We also assessed the behavioral adjustment of these participants and found heightened levels of maladaptive behavior for Evening-type adolescents.
In BD, studies have found heightened affective lability in both manic and mixed episodes (Henry et al. 2003), as well as traits during euthymic periods (Henry et al. 2008).
Also, SIRT7 expression level is found heightened in a large number of patients with human hepatocellular carcinoma (HCC), and knockdown of SIRT7 repressed growth in liver cancer cells (Kim et al., 2013).
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The last three years have featured dozens of reports of players in severe cognitive decline, and several studies have found drastically heightened rates of dementia among retirees.
In 2002, the Women's Health Initiative study found a heightened risk of breast cancer and heart disease among women who used a common hormone therapy.
As scientific studies and anecdotal evidence have found a heightened risk for brain damage, dementia and cognitive decline in retired players, the league has faced barbed criticism from outside experts and, more recently, from Congress over its policies on handling players with concussions.
The airport has made it more convenient for travellers to experience Tibetan culture without the exasperating bureaucratic barriers necessary to get into Tibet, which are non-existent here: during a visit in summer 2011, I found a heightened government presence, but no restrictions, permit hassles or need to travel with a group.
The rebellious spirit we found there heightened our sense of the righteousness of our convictions".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com