That chance came last year when Affymetrix decided to set up a company to use its gene chips to find genetic differences between people that contribute to disease and to sell such information to drug companies.
DNA chips can be used to find genetic differences between people who respond to a drug and those who do not, starting in Phase II, or mid-stage, clinical trials.
Mycobacterial Genome Divergence Database (MGDD), allows to find genetic differences between two strains or species of M. tuberculosis complex [ 21].
When an assembly is available, the most common first task is to compare it against a reference genome (or another assembly, if no such genome is available) in order to find genetic differences between the newly assembled and reference genomes.
Researchers found significant genetic differences between the two groups.
In 2001, Alfred Roca and colleagues published a landmark paper on elephant genomics in Science, which found distinct genetic differences between forest and savanna elephants.
Using three different methods, traditional pair-wise genetic distance analysis (FST; Table S1), landscape genetic analysis (Fig. 1b), and Bayesian genetic clustering (Fig. 2), we found significant genetic differences between sample locations in all four species.
We found limited genetic differences between pre-drought ancestors and post-drought descendants, indicating that the two populations did not become more genetically similar, despite a greater overlap in reproductive timing after the drought.
However, using both mtDNA and ncDNA, we found no genetic differences between the southern 'intermediate' group, and the M. albomaculatus from the northern part of the lake, and therefore no evidence of support for the hybridisation hypothesis of Vreven and Snoeks [ 25].
We find large genetic differences between all three groups that cannot be explained by population continuity alone.
