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On BCI, mature trees (>10 cm dbh) are found at a frequency of 5 per hectare, in Ecuador at 0.7 per hectare and in French Guiana at 0.4 per hectare.
Accordingly, the Kdr allele, which confers resistance to pyrethroids, was found at a frequency of 8% in the An.
Using the IncA/C reference plasmid pRA1 as helper plasmid, E. coli SGI1-C transconjugants were found at a frequency of around 10−3 (Table 2).
Four triplets and one quadruplet in EGFR were found at a frequency of 0.3% (5/1627) of lung cancers with mutations prior to treatment with tyrosine kinase inhibitor (TKI) (Table 4).
Interestingly, a large number of polymorphisms were found at a frequency of 20% or greater (Figure 1), which is in distinct contrast to polymorphisms found in coding regions of membrane transporters [10].
The 7-marker haplotype negatively associated with height was found at a frequency of 6.6% in the VB cohort, and had a frequencies of at least 1% in the European diversity panel (Haplo_365).
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In Mexico, genetic rearrangements (such as ETV6/RUNX1) that have a good prognosis have been found at a frequency below those of developed countries [ 38], whereas genetic rearrangements with a bad prognosis have been reported at a higher frequency [ 38].
In average, 171 genera were found at a frequency above 0.01%, accounting for 99.4% of the global diversity.
These interactions are complex; considering alleles with a relative risk for breast cancer of 1.5 and found at a population frequency of 30%, it has been estimated that an individual would need 33 to 40 such risk alleles to explain a threefold increased risk of breast cancer [ 21].
Here the susceptible allele is derived, but is nevertheless found at a global frequency of 23% and appears to have spread recently, perhaps suggesting the action of selection at a linked locus [ 30 ]. Polymorphism in the antiviral RNAi pathway (Dicer-2) has also been proposed to underlie some of the genetic variance for resistance to Dengue virus in the mosquito Aedes aegypti [ 31].
In particular, this haplotype is found at a genotypic frequency of 8% in the 1,000 Genomes Nigerian Yoruba (YRI) population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com