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A study in Malawi that evaluated the impact of H. influenzae vaccine found a marked decrease in the prevalence of invasive H. influenzae infection after vaccine introduction.
We found a marked decrease in the susceptibility rates for ciprofloxacin over a relatively short time period (from 47% in 1997 to 16% in 1999); 3.6% of all isolates were resistant to levofloxacin.
In Finland, results of a recent field trial found a marked decrease in the incidence of invasive pneumococcal disease among children who were vaccinated according to a 3+1 or a 2+1 immunization schedule; vaccine effectiveness reached 100%9595% CI 83%1000%) and 92% (95% CI 58%1000%), respectively, after 2 years (24 ).
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Interestingly, we found a marked decrease in LINE-1 methylation in most of the studied cell lines (Figure 4).
Regarding the presence of dyslipidemia, we found a marked decrease in its prevalence (40.6% vs 30.3%, P<0.001).
Because it is known that biotransformation of CCl4 is mainly mediated by CYP2E1 [29] 29], we further analyzed the hepatic expression levels of this cytochrome and found a marked decrease in response to CCl4 treatment.
In additional experiments we found a marked decrease in SPIO-generated signal voids from proliferating labeled hBMSCs over a period of 14 days in vitro, representing 5 6 cell divisions (data not shown).
We found a marked decrease in keratometry with age, and an increase in CCT with age.
We found a marked decrease in SETD2 levels correlating with higher stages of tumour.
We found a marked decrease in EGFP expression in peritoneal cells, suggesting that AP20187 can deplete circulating BM-derived microglia in rd7/rd7 Tg/Tg mice (supplementary material Fig. S2A).
Interestingly, in MCF10A cells expressing farnesylated Akt1 we found a marked decrease in sensitivity towards both, cisplatin and doxorubicin, but consistently not towards paclitaxel (data not shown).
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