However, our experiments foster the hypothesis that lack of Treg function and the consequent lack of peripheral tolerance lead to systemic autoimmune features resembling those in SLE.
The results of these experiments therefore fostered the hypothesis that the PB1-F2 proteis is not forming canonical protein mediated transmembrane pores.
A statistically relevant increase in both IL-6 and HMGB1 serum levels at 24 h after surgery fosters the hypothesis that serum post-operative HMGB1 derives, at least partially, from monocytes and exhibits the potential to trigger IL-6 secretion.
However, insect activity had substantially declined after td 45 when SA 8 became infected (data not shown), which fosters the hypothesis that mechanical transmission by insects may play a role in B. besnoiti transmission [ 2, 37, 38].
Studies demonstrating strong, socially recognized motivations for reproduction and the care of children distinct from sexual activity further dissuade from the simplicity of this hypothesis (Foster 2000; Rotkirch 2007).
Taken together, these considerations foster the interesting hypothesis that besides a role in controlling mtDNA copy number and ROS production, Mpv17 may be functionally linked to components of the extracellular matrix or of the cytoskeleton, which are involved in the integrity of the GBM and possibly other epithelial basement membranes in vertebrates, notably mammals.
Such a lack has considerably hampered functional studies and has fostered therefore the hypothesis that DING proteins isolated from eukaryotes were in fact prokaryotic contaminants.
Later studies revealed that combination infliximab plus MTX tended to be superior to monotherapy [ 31], dramatically affected joint damage [ 32] and inhibited joint damage even in the absence of a clinical response, thus fostering the dissociation hypothesis (see Early rheumatoid arthritis, below) [ 33].
This study contributes to L2 writing research which seeks to tie predictions of the Limited Attentional Capacity Model (Skehan, 1998; Skehan & Foster, 2001) and Cognition Hypothesis (Robinson, 2001, 2005, 2011a, 2011b) to models of working memory in L1 writing (Kellogg, 1996).
