Furthermore, as written text is not an interactive medium, it fosters differentiation and separation at the cost of cooperation.
In vitro, the reduction of Oct3/4 expression fosters differentiation of ES cells into trophectoderm, i.e., placental lineage, whereas the overexpression of Oct3/4 promotes differentiation into primitive endoderm and mesoderm [19].
Perfusion, in contrast, seemed to foster hematopoietic differentiation within the 3D scaffolds, as seen by the expression of CD71, a marker specific for erythroid progenitors.
Our findings with a novel photocrosslinked hyaluronic acid (HA) hydrogel suggest that stiff gels (high HA concentration, 5% w/v) foster chondrogenic differentiation and matrix production, but limit overall functional maturation due to the inability of the formed matrix to diffuse away from the point of production and form a contiguous network.
The imbalance is caused by enhanced expression of inflammatory cytokines, such as tumor necrosis factor (TNF), which foster the differentiation of osteoclasts and hamper formation of osteoblasts.
IMPACT: Our findings suggest that SIRT1 may be a therapeutic target to foster MSC differentiation to preserve integrity of MSC-derived tissues in aging animals.
It is likely that dendritic cells and inflammatory monocytes predominate in the case of sepsis, whereas osteoclastogenic cytokines foster OC differentiation in inflammatory arthritis.
Toll-like receptor signaling, leading to MyD88 signaling, is another innate immune signal fostering Th17 differentiation [ 43].
During development, feedback from growing populations of cells, reduces the effective dimensions of gene expression, thereby fostering terminal differentiation.
