For example, it would be of interest to examine the pattern of Fos expression in rats trained on discrete-trials temporal generalization tasks [2].
Regional Fos expression was compared between rats trained on the FIPP and rats trained on a variable-interval (VI) schedule matched to the FIPP for overall response rate and reinforcer delivery.
► Fos expression in the striatum did not differ between rats trained on the two tasks.
Although the level of Fos expression in the DLCP was somewhat higher in rats trained under the FIPP than in those trained under the VI schedule; however the difference did not attain statistical significance.
However, there was no significant difference between the levels of Fos expression in the dorsal or ventral striatum of the rats trained under the two schedules.
It is possible that the lack of a significant effect of the timing task on striatal Fos expression in the present experiment may reflect the relatively high rates of operant responding seen in the rats trained under both schedules.
Multiple comparisons with the control (deprivation-only) group indicated that the rats trained under the adjusting-delay schedule, but not those trained under the adjusting-magnitude and no-delay schedules, showed enhanced Fos expression.
Multiple comparisons with the control (deprivation-only) group indicated that the rats trained under both the adjusting-delay and adjusting-magnitude schedules, but not those trained under the no-delay schedule, showed enhanced Fos expression.
In contrast, experimental models of resistance training (e.g., functional overload (FO) of the plantaris muscle) are associated with increased percentages of slower MHC isoforms [ 16].
In fact, c-fos is induced in dentate gyrus neurons that, following spatial memory training, are recruited into spatial memory circuits [34], [70].
