Sentence examples for forward screening from inspiring English sources

Mutant lines identified by forward screening can be used to develop functional markers for marker-assisted breeding.

Forward (screening for phenotype) and reverse (screening for activity against a selected protein) chemical genetics, by combining medicinal chemistry, biological screening and combinatorial synthesis techniques, has enabled us to address previously intractable problems.

We propose to engineer HRP by directed evolution or semi-rational protein design, express HRP in the periplasm of E. coli allowing straight forward screening for improved variants, and finally produce these variants as IB in high amounts, which are then refolded.

To date, mostly forward screening approaches have been used in wheat to identify mutants (http://wheat.pw.usda.gov/GG2/Triticum/wgc/2008/).

Genotyping of the 41 selected mutants for forward screening (Figure 2B) revealed four new highly Fe toxicity-tolerant mutants, Mu1463, Mu3130, Mu11183 and Mu783.

For Fe toxicity screening, 4,500 lines were randomly chosen for forward screening while 500 pooled DNA libraries (representing 24 M1 plants per pool) from the M4 generation were used for reverse screening (Figure 1). Figure 1 Schematic view of mutant discovery for rice mutant tolerance to Fe toxicity by reverse and forward genetic screens of a large FN-treated population.

In a number of different labs mouse forward screens have been conducted and shown to be a fruitful method for the identification of novel gene functions even in mouse [2], [3], [4], [5], [6].

When the closure was announced by the television company in March, Yorkshire Forward, Screen Yorkshire and Leeds City council stepped in to work on an emergency action plan.

Mutants from both reverse and forward screens suggested a role for OsFRO1 in seedling tolerance to Fe toxicity.

In the forward screen, we selected five highly tolerant and four highly intolerant mutants based on the response of seedlings to 300 ppm Fe.

Graudenz and Stralsund were assigned to the forward screen, while Kolberg and Rostock were assigned to the starboard and port, respectively.