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Of all the candidates identified miR181a is specifically put forward for further study in in-vivo mammalian models of induced hearing loss in light of its demonstrated proliferative effect in the chicken inner ear as well as the fact that a miRNA based therapeutic could potentially be locally delivered to the middle ear and passively absorbed through the round window.
So that the dose of 50 mg m−2 will be taken forward for further study.
Because neither of these molecules passed the in silico criteria, they were not taken forward for further study.
This analysis helps to prioritise those TFTRs that might be taken forward for further study of the regulatory mechanisms involved in survival of M. tuberculosis.
Similar(55)
Eleven of the clones exhibited strong neutralization potential (∼95% or higher) at 100 nM; among these, E10 and F4 had favorable expression yield, were well-behaved, and thus were carried forward for further studies as representative examples.
Finally, we put forward directions for further study.
There will be, going forward, a need for further study to better understand these results.
Given the abundance and nature of evidence for a role of miR181a, miR27a, and miR141/miR200a in cellular proliferation or inner ear development, we put these forward as particularly intriguing candidates for further study within the context of auditory hair cell regeneration.
The centers contacted the laboratory for further study and then forwarded the anthrax sample that arrived last week.
Though clearly there is much work to be done to move this hypothesis forward, there is sufficient evidence in the literature to make the case for further study.
Others called for further study.
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