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There is no hint of a calculation or empirical evidence showing that a de novo gene can arise fortuitously without involvement of selection.
Many enzymes possess small side activities which arose fortuitously (i.e. neutrally), which may be the starting point for the evolutionary selection of a new function.
Thus, the traditional view sees activity in the "junk" as random noise out of which adaptive material arises fortuitously.
However, many of these matches are unlikely to correspond to actual transcriptional loci, as tags may match more than one genomic site or may represent sequencing errors arising fortuitously from more abundant tags that match the genome elsewhere.
Arise, arise, arise!
Ambiguities arise.
Problems arise.
Contrarians, arise!
"Situations arise".
Paradoxes arise.
Disagreements arise.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com