We exploited a fortuitous experiment of nature to directly test this hypothesis: the TGF-β type II receptor gene is inactivated by mutation in nearly all colorectal carcinomas having microsatellite instability, as seen in hereditary nonpolyposis colorectal cancer (HNPCC) and in sporadic medullary colorectal cancers.
Therefore the chemical versatility of the amino acid alphabet underwritten by the universal genetic code was not the outcome of fortuitous happenstance but the result of nature's relentless search for excellence in protein performance.
Through mutually gained experience they were able to distinguish these signs from physical manifestations that were only accidental and fortuitous, dependent on a patient's individual nature, complexion, dwelling place, profession, age, astrological inclination, and so on.
We focus specifically on the efforts required to identify the leachables, and the fortuitous mixed mode separation mechanism and low concentration nature of the product, which were the main factors contributing to the unlikely detection of the leachables by SEC.
The fifth formulation leaves us totally mystified because the proponents of the fortuitous generation thesis have nowhere specified what this nature is by virtue of which an effect can occur without its cause.
And since in the realm of nature occurrences take place which are even contrary to nature, or fortuitous, the same happens a fortiori in the sphere swayed by custom, since in this sphere natural law is not similarly established.
Magical beliefs still persisted, however, until late in the classical period; thus, the prognosis could be affected by such fortuitous factors as the cleanliness of the messenger sent to fetch the physician, the nature of his conveyance, or the types of persons the physician met on his journey to the patient.
The demonstration of statistical significance in scientific articles and project reports is commonly a fortuitous outcome of arbitrarily chosen sample size in relation to sample variance and the nature of the experimental or managerial treatments, with no consideration of what constitutes a material difference.
So the "determinate intrinsic natures of the unique particulars," Dharmakīrti argues in PVT "are not accidental or fortuitous since what is not determinate cannot be spatially, temporally and ontologically determinate" (Tshad ma ce 179a).
Hence it appears that fortuitous hydrolysis of the ethyl ester moiety to generate a C-terminal carboxylate provides a unique structural insight into the nature of the oxyanion hole.
Fortuitous neurochemistry!
