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The effect of various formulations parameters on the physicochemical properties of the nanoparticles was investigated.
However, the quality of extrudates and tablets can be optimized by adjusting specific formulations parameters (e.g. drug load).
In max-margin formulations, parameters are optimized such as to drive them away from wrongly determined structures and toward correctly determined ones.
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The lipid nanoparticles were optimized for process and formulation parameters.
The formulation parameters modified the intrinsic properties of chitosan.
The formulation parameters did not affect the particle size of both the SLN formulations.
The formulation parameters of nanodispersions affect their characteristics, as do processing and environmental variables.
Hence, desirability criteria were used to find out optimized formulation parameters.
Initial in vitro experiments were conducted to optimize formulation parameters prior to transdermal delivery in rats.
Effect of formulation parameters such as polymer concentration and cross-linker concentration has also been evaluated.
Also, using experimental designs, statistical significance of the formulation parameters influence was estimated.
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