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Dry powder vaccine formulations are highly attractive due to improved storage stability and the possibility for particle engineering, as compared to liquid formulations.

In particular, convex problem formulations are highly desired since the global optimum can be obtained using well-developed technics, e.g., the interior-point methods (IPM) [10].

Substrate formulations are highly sensitive to both glucose and iron concentrations at the lowest enzyme concentrations.

These formulations are highly allergenic, require extensive premedication, and are responsible for most of the acute toxicities observed with taxane therapy, rather than the taxanes themselves.

According to Zager and colleagues [ 32], parenteral iron formulations are highly potent pro-oxidants that can induce tubular and endothelial cell death.

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In vitro drug release of the nanoemulsion formulations was highly significant (p < 0.01) as compared to marketed capsule formulation and drug suspension.

The drug formulations were highly efficient in inhibiting the growth of melanoma cells, with IC50 values significantly lower than melphalan, the drug currently used for the treatment of in-transit melanoma.

Congeners in the penta and octaBDE formulations were highly and significantly correlated within formulations [Spearman correlation coefficients (rS): pentaBDEs 0.79 to 0.997, octaBDEs 0.50 to 0.78] (see Supplemental Material, Table S4).

The authors concluded that the solubilization capacity of the formulations is highly dependent on the nature of the lipid used, and the predictivity of the in vitro lipolysis is dependent on the amount of lipid used in the experiment.

Compared with ara-C, NHAC in liposomal formulations was highly resistant to deamination, resulting in levels of formation of arabinofuranosyluracil 42 and ten times lower in plasma and liver microsomes respectively.

The plasma profiles of IntelliCap® and Mylan formulation are highly similar.

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