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The optimized formulation was calculated and examined.
Moreover, in order to detect possible dependencies, a COX proportional hazard model with factors gender, age, compliance and drug formulation was calculated for the parameter 'time to resolution of symptoms'.
The weight fraction of each ingredient in the formulation was calculated by means of Wi = 0.618n in phase 1, Wj=Wi + Wixrm /WF and Wj=Wi + Wixrm/Wf in phase 2 and Wj=Wi + Wixrm/(WF+Wf) in phase 3.
Theoretical release profile of drug for controlled release formulation was calculated and considered as reference for the determination of similarity factor (f2) and desimilarity factor (f1). RSM, f2 and f1 were used to select the optimum formulation.
From the graph, the IC50 value of the formulation was calculated as 5.51 μg/ml.
The cost for each formulation was calculated as the mean cost of HCP time (based on Pharmaceutical Management Agency hourly rates) plus the mean cost of consumables used.
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The ultimate strength of the damaged tanker, to be used in the formulation, is calculated by means of a specific structural code, in which the damage is simulated by the removal of the damaged elements.
Percentages of 1.1% (chemical standard) and 0.6% d-MTX (pharmaceutical formulation) were calculated by solving the above equations for y = 1.
FIC for P60 + CAF in both aqueous form and ME formulation were calculated as the MIC of an agent in combination divided by the MIC of that agent alone.
Thus gestational age-specific perinatal/neonatal mortality rates under this formulation were calculated with perinatal/neonatal deaths at any gestational age in the numerator and the fetuses at risk of perinatal/neonatal death at that gestation in the denominator.
Colonies having more than 50 cells were counted, and the percent colony inhibition (PCI) capacity of the formulations was calculated as follows: Number of colonies in UC untreated control PCI = − Number of colonies in formulations Number of colonies in UC × 100 Open image in new window.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com