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Recent advances in formulation technology can increase lung dose and reduce its variability.
The implications for the design of biocontrol inocula and formulation technology are discussed.
In vivo experiments in mice confirm that this vaccine formulation technology is capable of enhancing cellular immune responses.
The new device combined with NanoCluster formulation technology allowed convenient and efficient drug delivery through endotracheal tubes.
While a perfect DPI may never exist, both device and formulation technology are evolving to rectify perceived deficiencies in earlier systems.
In 2006, Dr. J. Milton Harris, a former professor at the University of Alabama, Huntsville, and Nektar Therapeutics, a company with which he was associated, agreed to pay the university $25 million to settle accusations that he had secretly patented valuable drug formulation technology.
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Recent advances in these formulation technologies have led to the successful commercialization of lipid-based formulations.
Over the years, different formulation technologies intended for gastro retentive dosage delivery were investigated and patented.
The evolution of respiratory therapeutics has created a need for flexible formulation technologies to engineer respirable particles.
Moreover, the emergence of novel excipients with acceptable regulatory and safety profiles coupled with advances in formulation technologies have greatly improved the potential for successful lipid based formulations.
Enabling formulation technologies are highly in demand for the successful development of various dosage forms for the effective delivery of peptide and protein drugs.
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