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First is the formulation of the model.
The numerical formulation of the model is described in detail.
The formulation of the model is motivated by the biological problem of detecting recurrent DNA copy number variants in multiple samples.
The formulation of the model has been consistently derived within a thermodynamic framework.
The mathematical and numerical formulation of the model is briefly sketched.
The formulation of the model makes it suitable for deterministic MINLP solvers.
The number of parameters were minimized by the dimensionless formulation of the model.
The formulation of the model on curvilinear coordinates is presented in the appendix.
An alternative formulation of the model which is parameterized by the rate of dilatation is proposed.
The general formulation of the model allows it to deal with a large number of energy-system structures.
This approach allows the mathematical formulation of the model (state representation) and the analysis of its dynamic response via simulation.
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