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The efficiencies of the generated designs from the two methods are generally very close and so we recommend the SDP formulation in practice.
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The open-label OBSEER study evaluated the effectiveness and tolerability of Equasym XL®, a MPH-MR formulation, in routine practice.
42 The availability of a U-200 formulation in clinical practice has the potential to enable higher doses to be administered in a given injection volume.
However, demonstrating equivalence of short-term efficacy and safety with a widely used comparator provides little insight into whether we need this or any other longer-acting or more concentrated insulin formulation in clinical practice.
This results in a reliance on off-label drug formulations in clinical practice [14].
Although non-adherent patients are typically the ones chosen for depot formulations in clinical practice, they are often reluctant to enroll in RCTs.
However, we have not come across studies which have attempted to document key actors' perspectives in regard to the barriers which attenuate the influence of CEA in policy formulation and practice in Sub-Saharan Africa. Sub-Saharan Africa
Since the above presented formulation is not applicable in practice, a reformulation by a Dantzig-Wolfe reformulation is a promising alternative.
Integration of these formulations in clinical practices based on universal precautions should help further minimize the risk of opioid abuse while fostering appropriate prescribing to patients with indications for opioid therapy.
Nevertheless using (a_{F}^{(3)}) in the variational formulation 8 seems to work in practice (see below).
However, in practice the formulation given can also contain diphtheria and tetanus toxoids (dTpa vaccine) [77].
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