From their model formulation, the basic block planning approach (Günther et al. 2006), was derived as a single-stage model formulation primarily for application in high-variant production systems with volatile demand.
These results will set the stage to develop antimicrobial nanoparticle formulations for applications in chronic wound treatment.
This formulation was considered to be the most appropriate formulation for ophthalmic application, and it was therefore used for further characterizations.
Benefits of the chosen formulation for industrial application are the ease of setting up the optimization model for arbitrary printer configurations, and the short computation times.
The in vivo skin toxicity studies and histopathology analysis showed absence of toxic lesions, which confirmed the suitability of the formulation for topical application.
These results identified the cilnidipine-HP-β-CD inclusion complex as an effective new approach to design a novel formulation for pharmaceutical application.
The aim of this investigation is to combine the advantages of pluronic® F127 hydrogels and nanoparticles composed of poly isobutylcyanoacrylate) (PIBCA) core coated with a mixture of chitosan and thiolated chitosan to design novel multifunctional formulation for mucosal application.
The characterizations of the prepared semisolid formulation for topical application on skin were assessed by means of particle size distribution, zeta potential analysis, X-ray analysis, in vitro percutaneous penetration, rheological study, skin irritation test, in vivo pharmacodynamic evaluation and in vivo pharmacokinetic study.
A lotion formulation containing DMSO and ethanol was the best vehicle for topical ALA delivery to papillomas, whereas cream was the most efficient formulation for He-ALA application.
