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Formulation differences were therefore evidenced only by male subjects.
Thus, formulation differences are relevant to microbicide tolerance and acceptability, and the 3-day trial design validated in this study can be used to assess formulations.
Formulation differences also occur between the original branded drug and the generic version.
Formulation differences have been noted in generic versions of antihypertensives [ 90– 92].
The magnitude of the effect varied between studies, possibly due to strain and formulation differences.
The review includes evaluation of information on: resource use and costs associated with switching, patient adherence and persistence with antihypertensives, patient satisfaction with switching, efficacy and safety aspects of ARBs and ACEIs, drug formulation differences, and guidelines for switching antihypertensives.
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Within each of these formulations differences in convergence were observed at different levels of PEVexact.
The discussion also focuses on the boundary-formulation differences between the proposed model and the documented temperature prediction models for concrete slabs.
The discussion also focuses on the boundary-formulation differences between the proposed model and the field test model for concrete slabs, which is highlighted in terms of how these models characterize the impact of temperature and moisture profile inside of pavement slab.
In cocrystal-Soluplus formulations, difference in drug release at 1 : 0.5 and 1 : 0.25 ratios was nonsignificantly different, while at 1 : 1 ratio in formulation CSS-1, total 83% drug release occurred.
Assuming a type I error rate (two-sided) of 0.05, an estimated standard deviation of 15.0, a correlation of 0.10 between the two study phases, and a 15%% loss to follow-up, 48 subjects were required to detect a between-formulation difference of 9.0 μmol h/L in the area under the curve for plasma lutein [ 16].
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