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However, formulation changes may alter the secondary, tertiary, and quaternary structures of IFNβ products.
"Changing the formulation, for whatever need, can impact [taste, texture and shelf life] and manufacturers need to understand the consequence of formulation changes and how to mitigate them," Butcher says.
Catalyst aging or formulation changes can cause a perturbation to the rate constant matrix of a monomolecular reaction system.
This helps explain why twin screw granulation is more robust with respect to formulation changes compared to high shear wet granulation.
This work analyzed three varied two-component systems, each showing different effects from composition on polymerization kinetics due to formulation changes in functionality, viscosity, and reactivity.
What happens if your raw material, finished product, or formulation changes?
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Normally considered a conservation grade material [17], this formulation change is an example of how acrylic + CN may be found together within an adhesive in the archaeological conservation context.
A formulation change in this kit made since the publication of several of the prior studies resulted in higher measured concentrations of sFlt1 than reported previously among low-risk pregnant women.
Adverse events reported from May to December 2008 relating to Eltroxin formulation change.
News story 1, which was the first television news coverage of the formulation change, had a dramatic impact on total symptom reporting.
Eprex is a human erythropoietin (EPO) which underwent a formulation change that was subsequently linked to increased antibody formation to the endogenous form of EPO.
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