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The simplified formula of the Modification of Diet in Renal Disease index (sMDRD) [ 15] was also calculated according to sMDRD = 186.3 × SCR -1.154 × age-0.203 age-0.203if black) × (0.742 if female) where serum creatinine was expressed in mg dL-1.212
simplified formula of the modification of diet in renal disease.
The creatinine clearance (CrCl) was assessed by the simplified formula of the Modification of Diet in Renal Disease (sMDRD) [19].
The creatinine clearance (CrCl) was assessed by the simplified formula of the Modification of Diet in Renal Disease (sMDRD) [ 19].
Estimated glomerular filtration rate (eGFR) was calculated using the formula of the Modification of Diet in Renal Disease study group [ 26].
The glomerular filtration rate was estimated using the formula of the Modification of Diet in Renal Disease study: 186 × [(serum creatinine)−1.154 × (age)−0.203 × (0.742, if female) × (1.210, if African descendant)] (11).
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In this study, estimated GFR (using the LBM-adjusted Cockcroft and Gault formula or the formula derived from the Modification of Diet in Renal Disease [MDRD] study [ 23, 24]) was higher in RA patients as compared with healthy volunteers (MDRD-derived GFR: 123.9 ± 14.2 versus 77.2 ± 8.1 ml/minute per 1.73 m; p = 0.0015).
Early stages of renal dysfunction are assessed through laboratory monitoring of creatinine and glomerular filtration rate is calculated using either the Cockcroft Gault formula or the modification of diet in renal disease (MDRD) calculation.
Glomerular filtration rate (GFR) was estimated using the formula from the Modification of Diet in Renal Disease (MDRD) study (7).
GFR was estimated using the four variables formula from the modification of diet in renal disease study (MDRD) [ 15].
The most accurate results are obtained with the Cockroft Gault equation, whereas the most precise formula is the Modification of Diet in Renal Disease (MDRD) study equation.
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