Sentence examples for forms of the epimerase from inspiring English sources
These forms of the epimerase provide two advantages.
Wild type GNE forms homo-hexamer in solution [10], and allosteric regulation of the epimerase and kinase activities of GNE is important for the normal function of the protein [10], [11].
We have solved the crystal structures of the apo-forms of DAP epimerase mutants (C73S and C217S) from Haemophilus influenzae at 2.3 Å and 2.2 Å resolution, respectively.
The location of the epimerase and epoxide hydrolase varies somewhat, the epimerase ORF being usually between the nitrilase and the epoxide hydrolase ORFs.
It was established that the 2-OH of ribose is oxidized to decaprenylphosphoryl-2-keto-β d- erythro-pentofuranose, which is then reduced to form DPA. These activities are encoded by Rv3790 and Rv3791, respectively, and the simultaneous expression of both is required for complete activity of the epimerase reaction (Mikusová et al., 2005) (Fig. 3).
Reducing the size of the epimerases enables the epimerization of otherwise inaccessible regions in the alginate polymer.
The distribution and nucleotide composition of the epimerase-III-encoding genes (Table 2) do not allow us to infer the time of this transfer event.
Both the soluble and immobilized forms of double-tagged 2-epimerase-5D were effective for the epimerization of GlcNAc and ManNAc.
The DSZS AT was titrated from 0 to 1 μM in the presence of equimolar concentrations of malonate and methylmalonate (1 mM each); these diacids were converted in situ into racemic forms of their corresponding CoA monothioesters using the Streptomyces coelicolor MatB and methylmalonyl-CoA epimerase enzymes, as before.
The mutations are located at either the epimerase domain or the kinase domain [13] and lead to hypoactivity of the enzyme [11].
