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Because biological invasions are perturbations of natural systems they provide excellent opportunities for both natural and manipulative experimentation with potential for a range of forms of replication.
Prion replication is nevertheless subject to occasional epimutation and then natural selection just like other forms of replication.
Although all forms of replication have value, they are not all equally common.
This activity is required for robust activation of Cds1 in response to HU treatment and other forms of replication stress.
However, there remains debate as to which form of mtDNA replication predominates and even whether different forms of replication occur in different tissues.
Brc1-defective strains are sensitive to genotoxins that stall replication forks or create DNA lesions that lead to replication fork collapse or other forms of replication stress (Sheedy et al. 2005).
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Under stationarity, observations of a single realization of the random function at different positions can be treated as a form of replication.
While private companies would obviously still be free to conduct business as usual, the push by corporate data scientists to publish in the academic literature would mean that even major portions of their work would make its way through rudimentary review and be forced to offer at least some form of replication data.
"The result of this form of replication across cities is the wholesale denial of the very idea of locality," says Picardi. "Regenerated areas become separate, exclusive enclaves no longer interwoven with the city fabric and local built environment.
Additional support, in the form of replication using other despotic species and comparisons with less despotic macaques, is needed.
Our screen, by virtue of incorporating multiple concentrations of oligomycin and examining the trend of response, contains an intrinsic form of replication.
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