Thus, translational research in pediatrics is not only necessary for new drug moieties, but also for approved pharmaceuticals used frequently without regard to dosage forms and formulation properties, both of which could significantly affect their bioavailability, plasma concentrations and therapeutic effect.
Determining the issues with current products and finding creative solutions using form and formulation to produce an improved product has been recognized as a true "win-win" in lifecycle management.
EN is not free of mechanical, gastrointestinal, and infectious adverse events, which may be avoided or minimized through the adequate nutritional planning (including suitable choice of enteral access and placement, administration form and formulation design) and strict patient monitoring.
As such, information such as the specific strength, dosage form, and formulation of a drug can be linked to each drug claim of a patient.
In this review, we explore the mechanisms that are responsible for the specific antioxidant properties of HSA in its native form, chemically modified forms, and commercial formulations.
The printing of active-polymeric fibers provides an innovative approach to develop tailored pharmaceutical dosage forms (shape, size and formulation) with minimal excipients.
The applicability of the developed methods was evaluated through the determination of ALD in pure form and tablet formulations.
A survey of the literature reveals that there is no method available for the determination of ETD in pure form and pharmaceutical formulations by oxidation-reduction reactions.
Three simple, fast and sensitive spectrophotometric methods were proposed for the quantification of doxepin hydrochloride in pure form and drug formulations.
The proposed methods are suitable for the determination of ETD in pure form and pharmaceutical formulations without interference from excipients such as starch and glucose, suggesting potential applications in bulk drug analysis.
