These mutations thus seem to represent a very early event, affecting a common glial precursor cell, and may in fact form a prerequisite for the t(1 19) translocation leading to 1p/19q co-deletion and oligodendroglial tumor development.
The results reveal that when the participants talked about having successful day-to-day routines, they experienced a basic sense of assurance which formed a prerequisite for moving from existential uncertainty to existential certainty.
The reason might be a too low plasma concentration of applied LPC resulting in complete binding and neutralization by serum proteins and consequently reduced bioavailability of the free unbound form, a prerequisite for their biological effects including IL-8 upregulation [11,30] (Fig. 2B).
Disintegration of oral solid dosage forms is a prerequisite for drug dissolution and absorption and is to a large extent dependent on the pressures and hydrodynamic conditions in the solution that the dosage form is exposed to.
The sequence information we obtained forms a useful prerequisite for study of expressed α-gliadin mRNA and determination of both their genome of origin and their epitope content.
Expression of enzymatically active GrB in recombinant form is a prerequisite for functional analysis and application of GrB for therapeutic purposes.
This work forms an essential prerequisite to the use of such sonars for quantitative measurement of backscatter, such as for echo-integration surveys and individual school density and biomass estimation.
These proteins remain linked via a disulfide bond (Skehel and Waterfield, 1975), which forms a hinge, a prerequisite for viral envelope fusion during entry (Klenk et al., 1975; Lazarowitz and Choppin, 1975).
Preparation of a rigid form, i.e. a specifically locked conformation, is a prerequisite for protein crystallisation.
HMGB1 that is actively secreted by activated macrophages or passively released from necrotic cells signals via TLR4 since the TLR4-binding epitope of the HMGB1 molecule expresses its cysteine in position 106 (C106) in reduced form, which is a prerequisite for activation of this signal pathway [ 47, 13].
