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They determined that leptin causes cultured endothelial cells to aggregate, forming tubes that resemble the early stages of blood vessels.
Littleton reacted to this discovery by turning to simple, clean shapes in 1968, forming tubes, rods and columns of glass that he cut and grouped together on bases of plate glass or steel.
PGF was detected in peripheral cells of the pre-retinal membranes (Fig. 8a arrow) and in cells forming tubes, resembling vascular cells (Fig. 8a magnified).
Firstly, we describe that HIP is downregulated in HAEC forming tubes on Matrigel.
Images of forming tubes were captured after 12 hours of incubation using a Spot-camera-equipped inverted microscope.
In multi-cellular systems involving pericytes, astrocytes, and EC newly forming tubes have the three dimensional structure of a vessel and exhibit both a lumen and tight junctions.
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The theoretical forming limit diagram (FLD) is also applied to analyze and predict the fracture trend of forming tube.
The resulting monolayer of neural precursor cells, forming tube-like rosette structures, was passaged up to three times for expansion.
Parental SH-IN cells gathered together under the differentiating medium without forming tube-like structures (Fig. 5a, right panel).
Forming tube-like structure which is an important indicator of endothelial function was measured in ASCs, early EPCs, and ELCs as previously described [ 19].
Pro-angiogenic function was enhanced, as cells readily formed tubes.
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