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There are also other formidable roadblocks to change.
Other scholars say the state efforts, if pursued in the courts, would face formidable roadblocks.
Rules restrain arbitrary behaviour, but they also can provide formidable roadblocks to achievement.
In his Science paper, Keasling discusses the formidable roadblocks that stand in the way of a future in which microorganisms and molecules can be tailor-made through metabolic engineering, including the need for "debugging routines" that can find and fix errors in engineered cells.
Yet, even with such forward-thinking leaders working on the cause, the fight for equality often required serious collective soul-searching among advocates who faced formidable roadblocks and setbacks along the way.
Majority Leader Harry Reid has promised an "open as possible process" for amendments, which means creating a path to citizenship for the estimated 11 million unauthorized immigrants still hasn't cleared two formidable roadblocks in Sens. John Cornyn and Ted Cruz, who respectively are insisting upon a totally secure border and no path to citizenship.
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The Senate presents a particularly formidable roadblock.
That threw up an unexpected and potentially formidable roadblock.
But in the Senate, the bill faced a formidable roadblock in Mr. Gramm.
Another formidable roadblock to the development of a substantive law of contract was the dominant role of the jury in a lawsuit.
Now, for law-enforcement officials, Gotti represents the most formidable roadblock left in a campaign to dislodge the Mafia from its remaining stronghold - the New York region.
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CEO of Professional Science Editing for Scientists @ prosciediting.com