To discover the core rhythmogenic and premotor interneurons that comprise CPGs and establish their functional parameters remain formidable problems, particularly in mammalian systems.
When intending to define best models of OLP reactivity and host HLA genetics that are associated with relative HIV control, this considerable number of parameters poses a formidable challenge for the necessary in-depth analysis.
This, however, is a formidable task, as demonstrated by numerous laboratory parameters compiled from the same patients we analyzed in this study [10].
Adelaide rapper Tkay Maidza has risen to the status of one of Australia's most exciting exports, applying her formidable flow to dance production that extends beyond the parameters of hip-hop.
As CLM includes numerous sub-models and associated parameters, the high-dimensional parameter space presents a formidable challenge for quantifying uncertainty and improving Earth system predictions needed to assess environmental changes and risks.
However, the number of parameters at play, and their complex interactions, presents a formidable challenge in delineating how the decisions of cell fate are orchestrated within the niche.
The increasing complexity and permanent growth of real-world robotics formidable challenges demand that most control systems be intelligently adaptive to the parameters and structures of dynamics.
Identifying the values of these parameters to obtain a validated, predictive model would be a formidable challenge.
However, MFD is a parametric hypothesis method from the statistic view, so the sensing performance is susceptible to the parameters' value setup; the determination of parameters' value is a much more formidable undertaking, and the accuracy of MFD may degrade significantly under time-variant multipath flat-fading (TVMFF) channels which are common in the next-generation communication systems.
The standard errors of the thus obtained parameter estimators can in principle be determined by simulation, but the associated computations are formidable.
