The enormous diversity of proteoforms produces tremendous complexity within cellular proteomes, facilitates intricate networks of molecular interactions, and constitutes a formidable analytical challenge for biomedical researchers.
Indonesia's diversity is formidable: some thirteen and a half thousand islands, two hundred and fifty million people, around three hundred and sixty ethnic groups, and more than seven hundred languages.
Everyone I spoke to highlighted L.A.'s formidable resources: great universities, cultural diversity, weather.
The immensity of T cell diversity presents a formidable challenge to its study and the aforementioned techniques lack sufficient depth of coverage (ability to detect low-frequency clones) and resolution (lack of sequence information without additional cloning steps).
Due to their large size and structural diversity, biopharmaceuticals represent a formidable challenge regarding analysis and characterization compared to traditional small molecule drugs.
These factors have not been evaluated systematically, but identification of such factors presents a formidable task, considering the complexity and diversity that constitute individual tumor and tumor host environment.
Channel 4 has the formidable Baroness King leading its equality and diversity practice and, behind the scenes, it has also tried to tackle some aspects of production where women are under-represented.
Large healthcare databases covering a total population of over four million from three countries were investigated— a formidable challenge in itself because of the diversity in healthcare and disease coding practices.
The enormous diversity of HIV-1 presents a formidable challenge for developing an effective AIDS vaccine.
HIV vaccine developers face formidable scientific obstacles, including the virus's genetic diversity and the lack of a clear understanding of the correlates of protective immunity in HIV infection (9 ).
