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The former sequence contains strong texture, while the latter does not.
The former sequence is optimal in that the experimentation can stop whenever the current model is deemed adequate and experiments already conducted could be considered necessary.
In this event, the small-amplitude ESWs with small spatial structure observed in the former sequence indicate the electron holes in the early nonlinear evolution process (e.g., Omura et al. 1996; Miyake et al. 1998; Umeda et al. 2002), which indicate that the ESW series with small amplitude may also be closer to the generating site.
For example, the sample crossover described in the Introduction between the haplogroup X2a sequence (sampled from the Ojibwa) and the haplogroup F1a1 sequence (from the Yakut) led to a displacement of two transitions (A4732G and G5147A) of total score 3.0 from the latter to the former sequence.
The former sequence was found in MfZPB from A54, and the cleavage site was S53/A54 (site-B1, Figure 5A).
Whenever a particular sequence is found to be dominated by another sequence, the domination rank of the former sequence is lowered.
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This is due to the fact that the former sequences were recorded at a much higher frame rate and contain more temporal correlation.
This method represents an alternative choice to the use of pseudorandom numbers, provided that a special care is paid to keep sufficiently uncorrelated as well as uniform the former sequences.
Around the former sequences, a search with N(1) all of all single point mutants will find only lower fitness, whereas around the latter sequences, the search will find at least one with higher fitness.
Hereafter, we use the word "type" instead of "class" to avoid confusion between former sequence-based classifications and our functional classification based on C-terminal motifs and the capacity to bind ETO1/EOL proteins.
This suggests that the former sequences represent a gene that is subject to more evolutionary constraints, similarly to MSMP in vertebrates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com