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In our in vitro matrigel assay HC-ECs cultured alone formed organized tube-like structures.
In the presence of medium from ACC-M, UVECs formed organized elongated tube-like structures resembling capillaries with an extensive network.
In our model, in the presence of RMF, MCF7 cells formed organized acini containing polarized cells and lumen, as well as elongated structures with features that resembled ducts.
Interestingly, depletion of either nephrocystin-1 or nephrocystin-4 in MDCK cell lines led to severely disorganized structures containing multiple lumens when grown in type-I collagen compared with control MDCK cell lines which formed organized, single-lumen structures (Fig. 5A).
In approximately 25% of the patients, the synovial tissue contains cellular infiltrates that have formed organized structures resembling structures normally observed in lymph nodes, comprising follicular dendritic cells (FDCs), with distinct T-cell and B-cell areas, therefore referred to as ectopic lymphoid structures.
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These complexes form organized arrays that can be modified by receptor expression and ligand levels, indicating that they are dynamic structures.
That is, humans have limitations that force us to specialize and form organized teams to cover the needed knowledge base to master difficult problems.
Here we show that the membrane-binding domains of two conserved clathrin adaptors, Sla2 and Ent1, co-assemble in a PI 4,5 P2-dependent manner to form organized lattices on membranes.
In 1963, the Alaska Legislature passed the Mandatory Borough Act, which required the eight most populous areas of the state to form organized boroughs by 1964.
C. gattii readily colonized scratch-wounded A. thaliana leaves on live plants forming organized layers of fungal cells with unique extracellular fibrils emanating from and between them.
The inability of Pycard−/− mice to form organized granulomas and the reduced presence of lung dendritic cells indicates a breakdown in host defense against Mtb.
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