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Appropriate matrix formation, turnover and remodeling in tissue-engineered small diameter vascular conduits are crucial for their long-term function.
As outlined in Charles Darwin's last book The Formation of Vegetable Mould through the Action of Worms (1881), earthworms are extremely important in soil formation, turnover, aeration, drainage, organic matter breakdown and incorporation, and nutrient availability.
FAK, for example, activates multiple intracellular signal transduction pathways that modulate actin filament formation, turnover of cellular-ECM adhesion complexes, formation of lamellipodia, and expression of matrix metalloproteinases; all processes that are involved in tumor cell invasiveness and migration [17], [18], [19], [20].
E-cadherin endocytosis and recycling is important for cell-cell junction formation, turnover and maintenance [ 18].
KLK5 and KLK7 are involved in keratinization, stratum corneum formation, turnover and desquamation of the skin, via degradation of the cell adhesion glycoproteins, corneodesmosin and plakoglobin [ 59– 61].
ADFP is associated with early stages of adipocyte differentiation and may play a critical role in regulating the formation, turnover and metabolic consequences of fat formation in mammalian extra adipose tissues [ 42].
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We report that Coronin 1B interacts simultaneously with Arp2/3 complex and Slingshot (SSH1L) phosphatase, two regulators of actin filament formation and turnover, respectively.
Actin filament formation and turnover within the treadmilling actin filament array at the leading edge of migrating cells are interdependent and coupled, but the mechanisms coordinating these two activities are not understood.
The role of S-nitrosothiol (SNO) formation and turnover in governing NO-related bioactivity remains uncertain.
Formation and turnover of kelo trees, as an outcome of natural forest dynamics, is an extremely slow process.
According to Christenson R.H. [24], the bone structure, metabolism, and regulation are reflected by markers of resorption, formation, and/or turnover.
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