Your English writing platform
Discover LudwigSuggestions(5)
Exact(3)
The binding of ubiquitin to ubiquitin docking sites in E3 ligases is suggested to play a role in ubiquitin chain formation specificity by bringing a specific ubiquitin lysine residue in close proximity of the ubiquitin thioester bond (Deshaies and Joazeiro, 2009).
Consequently, the RBR-LDD in the C-terminus of HOIP is sufficient for the linear ubiquitin chain formation specificity of the LUBAC E3 and does not require the presence of other LUBAC subunits.
Considering the culture as the gold standard, sixty-four of 65 patients with TB had the presence of cord formation (sensitivity of 98%) and 30 of 31 patients with NTM disease had non-cord formation (specificity of 96%) by the visualization of the aspect of the colony.
Similar(57)
The mechanism of progene formation presumes specificity of the interaction between Aa linked to the 3rd nucleotide, and DN (Fig. 1).
Further, switching the position of the cysteine and the methionine involved in the cross-link also abolished thioether bond formation, demonstrating specificity of SkfB for the directionality of the thioether linkage.
With respect to specific genes, CNS-core DHSs are located near many genes highly expressed in the nervous system, including those known to be involved in synapse formation and specificity (for example, Dscam, Dscaml1, complexins, contactins [ 26, 27]) and other neuronal processes (Additional file 2: Figure S2C).
A possible mechanism for this homocysteine-specific specificity involving the formation of a homocysteine-induced six-membered ring sandwich structure was proposed and confirmed for the first time by time-dependent fluorescence spectra, ESI-MS and EPR.
In the case of an apple core lesion or short wall thickening with shoulder formation and adenopathies specificity for a malignant tumour is 92% Open image in new window.
Catalytic RNAs might not have needed to evolve such a regulation mechanism due to the fact that their recognition strategy, which is based on base pair formation, provided sufficient specificity.
Future work will determine whether this newly identified region in XopD and/or the KAE-rich domain, related to dimer formation, determine the specificity of the DNA binding activity displayed by the XopD protein.
Briefly, nodule formation and host specificity are controlled by mutual signaling between the two partners.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com