Sentence examples for formation of tolerance from inspiring English sources

The study was designed to test whether intact vagal innervation of the liver is required for the formation of tolerance to lipopolysaccharide (LPS).

The study shows that prolonged infusion of low doses of LPS leads to the formation of tolerance and that vagal denervation of the liver by hepato-celiac vagotomy suppresses this process.

Protein tyrosine phosphatase non-receptor 22 (PTPN22) influences the development and activation of lymphocytes, innate cell-mediated immune host defense, formation of tolerance, and regulation of the immune system [[99]].

A key element in the formation of pathological microenvironments is the establishment of tolerance and cooperation between the different players, enabling an acute process to become chronicized.

The mechanisms of vagal control of the formation of LPS tolerance remain speculative.

In other words, the formation of salt tolerance is a cumulative process with stepwise changes in gene regulation.

Autoimmunity, which can include autoantibody formation, represents a breakdown of tolerance against self-antigens (Lleo et al. 2010).

Although the precise mechanisms governing the tumor-induced immune tolerance are still elusive, a constitutive activation of Stat3 in most tumors plays a crucial role in the formation of tumor-induced immune tolerance [6].

In susceptible mice and rats, injection of apoptotic cells results in loss of tolerance, autoantibody formation, and even clinical disease [ 6, 7].

12 13 Based on the results of research on various tissues during different stages of the disease, it may be possible to develop specific preventive interventions targeting the breaking of tolerance or the formation of autoantibodies.

These results suggest that nitrate tolerance is associated with decreased endogenous formation of hydrogen peroxide, which attenuates nitrate tolerance development.