Sentence examples for formation of mutant from inspiring English sources

Other changes, such as the formation of mutant cells, can do the same.

For instance, if IDH mutant:WT binding is weaker than mutant:mutant or WT WT binding, formation of the WT WT and mutant:mutant homodimers would outcompete formation of mutant:WT heterodimers.

While the importance of ER stress or proteosome malfunction in formation of mutant SOD1 aggregates has been established [35], [36], [40], the mechanisms by which mutant SOD1 forms LBHI/Ast-HI in FALS remain poorly understood.

The molecular mechanisms underlying the formation of mutant VAPB inclusions remain to be further determined.

(D – G ) NLK enhances the formation of mutant AR aggregates in a kinase activity-dependent manner.

Therefore, we were able to detect a 'neutral' effect on pedestal formation of mutant that mimics phosphorylation by Erk, while the Erk non-phosphorylatable form blocked pedestal formation.

Explanations for this finding might be either the formation of mutants of maspin [ 56] or the induction of maspin expression by chemotherapeutics [ 29] without a direct impact on tumor biology [ 48].

This large variation in network structure is achieved by the formation of shorter mutant filaments, which exhibit differing assembly kinetics and a manifestly reduced capacity to form the extended structures characteristic of the wild-type system.

Many functional proteins involving various metabolisms were likely to be responsible for the lesion formation of spl5 mutant.

To figure out whether the disrupted memory formation of silver mutant resulted from the abnormal development or the interference of physiological process of neural system, we acutely manipulated the expression of svr + transgene in adult flies with the TARGET system.

Indeed, while the kcat for PLP formation of this mutant enzyme was significantly decreased compared to wild type, it could be seen that there was also a significant increase in the KM for G3P with the E105D mutein, while no significant change was observed for R5P (Table 1B).