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Moreover, as described above, the Hippo/Taz/Yap pathway determines nuclear/cytoplasmic localization of active Smad complexes via cell density-mediated formation of Crumbs polarity complexes [ 18].
Importantly, the Hippo pathway, which senses cell density information, was recently found to determine nuclear/cytoplasmic localization of active Smad complexes via cell density-mediated formation of Crumbs polarity complexes and the transcriptional regulators TAZ and YAP [ 18].
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No, these diminutive star systems aren't stocked with small, furry-footed hominids, but their presence does confirm predictions that the formation of large galaxies left some crumbs on the table.
Fluorescence microscopy analysis confirmed the formation of continuous polymer-rich phase, the swelling of crumb particle and the compatibility between the modifier and bitumen.
A whole mountain of crumbs".
Each slice made a flurry of crumbs.
The crackle of crumbs flying up the vacuum cleaner.
Normally, White House watchers have a trail of crumbs to follow.
The core Crumbs complex in Drosophila consist of Crumbs, Stardust (PALS1 in mammals), PATJ, and Lin-7 (Bulgakova and Knust, 2009).
To identify potential additional Crumbs homologs, we searched the predicted C. elegans proteome for candidate homologs of Crumbs proteins by BLAST and HMMER.
The SAR is occupied by the Crumbs complex, composed of Crumbs (Crb), Stardust (Sdt), PATJ and Lin7, and the Par complex consisting of atypical protein kinase C (aPKC), Par6 and Bazooka/Par3 (Baz).
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